Niacinamide
melasma treatments
Niacinamide
melasma treatments

Niacinamide

Use Niacinamide (vitamin B3 topical treatment) as prescribed to help treat melasma and uneven skin tone by reducing pigment transfer in the skin, calming inflammation, and strengthening the skin barrier.
Niacinamide is a form of vitamin B3 that helps brighten skin by reducing melanin transfer to skin cells. It also strengthens the skin barrier and reduces redness, making it effective for melasma and post-inflammatory hyperpigmentation.
Niacinamide is suitable for all skin types, including sensitive skin. It is an excellent choice for those looking for a gentle but effective brightening agent.
Results may take 8–12 weeks of consistent use, with gradual brightening of dark spots and improvement in skin tone.
Niacinamide may be used by adults with melasma or hyperpigmentation, including those with sensitive or reactive skin. It is often included as part of a long-term maintenance regimen and is generally well tolerated. See pricing details here.

Real patients, real results

How effective is Niacinamide

Clinically supported results

Gradual improvement in skin tone and clarity with consistent use over time.*
Clinical studies show that Niacinamide helps reduce the appearance of dark spots, improve skin brightness, and support other melasma treatments when used regularly.
*In clinical studies, patients using niacinamide experienced visible improvement in pigmentation and skin texture within 8–12 weeks.
Niacinamide should be used as directed. For more details, see Important Safety Information.

How DermOnDemand Works

Common Question

Yes, Niacinamide is safe for daily use, either in the morning or evening. It can also be used twice daily for enhanced results.
Niacinamide is generally well-tolerated, but very sensitive skin may experience mild redness or irritation initially.
Yes, it pairs well with virtually all other skincare ingredients, including retinoids, vitamin C, and tranexamic acid, to boost results.