Apremilast

Apremilast is an oral medication used to treat moderate to severe plaque psoriasis by reducing inflammation inside the body that leads to redness, scaling, and plaque formation.

Customized prescription treatments for psoriasis within 24 hours
Prescriptions sent to your pharmacy (*often covered by insurance)
Convenient fast treatments 100% online

What is Apremilast, and how does it treat psoriasis?

Apremilast is an oral phosphodiesterase-4 (PDE4) inhibitor that reduces inflammation associated with psoriasis and psoriatic arthritis. It helps decrease the severity of plaques and joint pain.

Who is a good candidate for Apremilast?

It is ideal for individuals with moderate to severe plaque psoriasis or psoriatic arthritis who prefer an oral medication over injections or topical treatments.

How long does it take for Apremilast to work?

Improvements may begin within the first 2–4 weeks, with significant results typically seen by 16 weeks.

This treatment is prescribed for adults with plaque psoriasis who require systemic therapy or prefer an oral option instead of injections. It may also be suitable for patients who have not responded well to topical treatments alone. See pricing details here.

Real patients, real results

“Very happy to have been able to clear my skin conveniently from home.”

Samuel

DermOnDemand patient

“My cystic acne had been bothering me for a while, but now it's gone so thank you!”

Katie

DermOnDemand patient

“Acne annoyed me much of my life because of the constant visits to the dermatologist, now I can be treated from home.”

Talia

DermOnDemand patient

“DermOnDemand thank for making this possible to get great care for my acne without having to take off from work.”

Holly

DermOnDemand patient

“Feeling blessed with my clear skin that I finally achieved.”

Riley

DermOnDemand patient

How effective is Apremilast

Clinically proven results

Reduced plaque severity and improved skin clarity with continued daily use.*

Clinical trials show that Apremilast helps decrease inflammation and psoriasis symptoms, leading to clearer skin and improved quality of life over time.

*Noticeable improvement may be seen within 12–16 weeks of consistent treatment.

Apremilast should be taken only as prescribed. For more information, see Important Safety Information.

How DermOnDemand Works

01

Answer questions & submit photos

Quickly share your skin concerns by answering a few questions and uploading photos—it takes just 5 minutes.

02

Quick expert evaluation

Our dermatology team will carefully review your information, diagnose your condition, and create a tailored plan within 24 hours.

03

Personalized treatment

Your customized plan will be sent directly to you, and prescriptions (if needed) will go straight to your pharmacy.

Common Question

What are the side effects of Apremilast?

Common side effects include nausea, diarrhea, and headaches, especially during the first few weeks of use. These symptoms usually improve over time.

Can Apremilast be taken with other psoriasis treatments?

Yes, it can be combined with topical therapies or biologics under a dermatologist’s supervision.

Is regular monitoring required with Apremilast?

No routine lab tests are required, but your doctor may monitor your weight and mood, as the medication can sometimes cause weight loss or mood changes.