Dapsone

Use Dapsone (topical anti-inflammatory medication) as prescribed to help treat inflammatory acne, particularly red, swollen, or tender breakouts, by reducing inflammation at the skin level.

Customized prescription treatments for acne within 24 hours
Prescriptions sent to your pharmacy (*often covered by insurance)
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What is Dapsone, and how does it work for acne treatment?

Dapsone is a prescription-strength topical gel that works by reducing inflammation and targeting bacteria involved in acne development. It is particularly effective for inflammatory acne, including red, swollen pimples, and pustules. Dapsone also has mild antibacterial properties, helping to calm the skin and prevent further breakouts.

How should I apply Dapsone to my skin?

Apply a thin layer of Dapsone gel to the affected areas of clean, dry skin. Use it once or twice daily as recommended. Gently massage it in until it is fully absorbed. Avoid applying it to open wounds, severely dry patches, or areas with excessive irritation to prevent further discomfort.

What are the common side effects of Dapsone?

Mild side effects include redness, dryness, itching, or irritation at the site of application. These effects typically improve as your skin adjusts to the medication. Less commonly, some users experience peeling or flaking, which can be managed by using a non-comedogenic moisturizer daily.

Can Dapsone be used with other acne medications?

Dapsone can often be safely combined with other acne treatments, such as retinoids or topical antibiotics. However, it should not be used simultaneously with products containing Benzoyl Peroxide, as this can cause temporary yellow or orange discoloration of the skin. If you’re using multiple acne medications, apply them at different times of the day to minimize interactions.

Dapsone is intended for topical use only and may be prescribed for adolescents and adults with inflammatory acne. It should be used exactly as directed, and patients with known blood disorders or G6PD deficiency should discuss potential risks with their clinician before use. See pricing details here.

Real patients, real results

“Very happy to have been able to clear my skin conveniently from home.”

Samuel

DermOnDemand patient

“My cystic acne had been bothering me for a while, but now it's gone so thank you!”

Katie

DermOnDemand patient

“Acne annoyed me much of my life because of the constant visits to the dermatologist, now I can be treated from home.”

Talia

DermOnDemand patient

“DermOnDemand thank for making this possible to get great care for my acne without having to take off from work.”

Holly

DermOnDemand patient

“Feeling blessed with my clear skin that I finally achieved.”

Riley

DermOnDemand patient

How effective is dapsone

50–60%

reduction in inflammatory acne lesions has been observed with consistent dapsone use.*

Clinical studies show that Dapsone helps calm acne-related inflammation, leading to fewer inflamed lesions and improved overall skin appearance, especially in patients with sensitive or treatment-resistant acne.

*In clinical studies, patients using topical dapsone experienced measurable improvement in inflammatory acne within 12 weeks compared to placebo.

Dapsone should be used only as prescribed. For more details, see Important Safety Information.

How DermOnDemand Works

01

Answer questions & submit photos

Quickly share your skin concerns by answering a few questions and uploading photos—it takes just 5 minutes.

02

Quick expert evaluation

Our dermatology team will carefully review your information, diagnose your condition, and create a tailored plan within 24 hours.

03

Personalized treatment

Your customized plan will be sent directly to you, and prescriptions (if needed) will go straight to your pharmacy.

Common Question

How long does it take to see results with Dapsone?

Most users begin noticing an improvement in inflammation and redness within 2–3 weeks of consistent use. Significant results are typically seen after 8–12 weeks. To maintain clear skin, continue using Dapsone even after your acne improves.

Is Dapsone suitable for people with sensitive skin?

Yes, Dapsone is often tolerated by individuals with sensitive skin. However, if you experience significant irritation, reduce application frequency to once daily or every other day. A patch test on a small area can also help assess tolerance before widespread application.

Can Dapsone be used during pregnancy or breastfeeding?

Dapsone’s safety during pregnancy or breastfeeding is not fully established, but it is generally considered a low-risk topical treatment. It is minimally absorbed into the bloodstream, reducing the likelihood of systemic effects.

What should I do if I experience severe irritation or an allergic reaction?

Severe irritation is uncommon. If you experience persistent redness, swelling, or a burning sensation, reduce usage frequency and apply a hydrating, fragrance-free moisturizer. For more severe reactions, discontinue use temporarily.

Is Dapsone effective for all types of acne?

Dapsone is most effective for inflammatory acne, such as pimples, pustules, and cystic lesions. It may not be as effective for non-inflammatory acne, like blackheads or whiteheads. Combining it with complementary treatments can help address multiple types of acne.