Retinoid (Tretinoin)

Use topical retinoids as prescribed to help treat melasma and uneven skin tone by increasing skin cell turnover, dispersing excess pigment, and improving overall skin texture.

Customized prescription treatments for melasma within 24 hours
Prescriptions sent to your pharmacy (*often covered by insurance)
Convenient fast treatments 100% online

What is a Retinoid, and how does it help hyperpigmentation?

Retinoids, such as Tretinoin, are vitamin A derivatives that increase skin cell turnover. This process helps fade dark spots, improve skin texture, and enhance the effectiveness of other pigmentation treatments like Hydroquinone.

Who should use a Retinoid for melasma?

Retinoids are suitable for individuals with hyperpigmentation, melasma, or uneven skin tone. People with sensitive skin should start with a lower concentration and gradually increase.

How long does it take to see results with Retinoids?

Improvements in pigmentation typically appear after 8–12 weeks, with more dramatic results after 3–6 months of consistent use.

Retinoids may be prescribed for adults with melasma or hyperpigmentation, often as part of a combination treatment plan. They should be used under clinician guidance, especially for individuals with sensitive skin or those new to retinoid therapy. Retinoids are not recommended during pregnancy. See pricing details here.

Real patients, real results

“My dark patches have faded significantly, and my skin looks much clearer now.”

Sarah

DermOnDemand patient

“I struggled with melasma for years, but this treatment finally made a real difference.”

Jessica

DermOnDemand patient

“My complexion looks more even, and I feel confident going makeup-free.”

Lauren

DermOnDemand patient

“The pigmentation has lightened so much — my skin finally feels balanced again.”

Amanda

DermOnDemand patient

“I’ve seen steady improvement, and the results look very natural.”

Nicole

DermOnDemand patient

How effective are Retinoids

Clinically proven results

Gradual and sustained improvement in melasma and skin tone with consistent use.*

Clinical studies show that Retinoids enhance pigment fading and improve treatment response, particularly when combined with skin-lightening agents and daily sun protection.

*In clinical studies, patients using topical retinoids experienced visible improvement in melasma over 8–12 weeks, with continued benefits over time.

Retinoids should be used only as prescribed. For more details, see Important Safety Information.

How DermOnDemand Works

01

Answer questions & submit photos

Quickly share your skin concerns by answering a few questions and uploading photos—it takes just 5 minutes.

02

Quick expert evaluation

Our dermatology team will carefully review your information, diagnose your condition, and create a tailored plan within 24 hours.

03

Personalized treatment

Your customized plan will be sent directly to you, and prescriptions (if needed) will go straight to your pharmacy.

Common Question

What are the side effects of Retinoids?

Dryness, redness, and peeling are common during the first few weeks of use, but these symptoms usually resolve as the skin adjusts.

Can Retinoids be used daily?

Retinoids are often started at 2–3 times per week and gradually increased to daily use as tolerated by the skin.

Should I use sunscreen with Retinoids?

Yes, Retinoids increase photosensitivity, so sunscreen is essential to prevent further pigmentation or sun damage.