Tretinoin

Retin-A

Use Tretinoin (topical retinoid) as prescribed to increase skin cell turnover, help prevent clogged pores, and improve acne and overall skin texture.

Customized prescription treatments for acne within 24 hours
Prescriptions sent to your pharmacy (*often covered by insurance)
Convenient fast treatments 100% online

What is Tretinoin, and how does it work for acne?

Tretinoin is a topical retinoid derived from vitamin A. It works by increasing the turnover of skin cells, preventing the clogging of pores, and reducing inflammation. It also helps fade post-acne marks and improve overall skin texture, making it a cornerstone treatment for mild to moderate acne.

How long does it take to see results with Tretinoin?

Visible improvements in acne typically appear after 6–12 weeks of consistent use. However, initial worsening of acne, known as "purging," is common as clogged pores are cleared. Continued use helps achieve and maintain clearer skin.

Can Tretinoin be combined with other acne treatments?

Yes, Tretinoin is often combined with benzoyl peroxide, topical antibiotics, or oral medications for comprehensive acne management. However, care must be taken to avoid irritation from excessive layering of active ingredients.

Tretinoin is for topical skin use only and not meant for oral intake. Avoid using it on broken or irritated skin, and consult your clinician if pregnant or planning pregnancy about risks and proper use. See pricing details here.

Real patients, real results

“Very happy to have been able to clear my skin conveniently from home.”

Samuel

DermOnDemand patient

“My cystic acne had been bothering me for a while, but now it's gone so thank you!”

Katie

DermOnDemand patient

“Acne annoyed me much of my life because of the constant visits to the dermatologist, now I can be treated from home.”

Talia

DermOnDemand patient

“DermOnDemand thank for making this possible to get great care for my acne without having to take off from work.”

Holly

DermOnDemand patient

“Feeling blessed with my clear skin that I finally achieved.”

Riley

DermOnDemand patient

How effective is tretinoin

85%

of patients using tretinoin experience noticeable improvement in acne and skin texture with consistent use.*

The clinical results are clear: Tretinoin is a gold-standard topical retinoid shown to reduce acne lesions, unclog pores, and improve skin tone and fine lines over time by increasing skin cell turnover.

*In clinical studies, patients using tretinoin regularly saw significant reductions in acne severity within 8–12 weeks compared to placebo or non-retinoid treatments.

Tretinoin is for topical use only and should be used exactly as prescribed. It is not recommended during pregnancy unless specifically advised by a healthcare provider. For more details, see Important Safety Information.

How DermOnDemand Works

01

Answer questions & submit photos

Quickly share your skin concerns by answering a few questions and uploading photos—it takes just 5 minutes.

02

Quick expert evaluation

Our dermatology team will carefully review your information, diagnose your condition, and create a tailored plan within 24 hours.

03

Personalized treatment

Your customized plan will be sent directly to you, and prescriptions (if needed) will go straight to your pharmacy.

Common Question

What are the side effects of Tretinoin?

Common side effects include redness, peeling, and dryness, particularly in the initial weeks of use. These symptoms typically subside as the skin adjusts to the medication. Using a gentle moisturizer and sunscreen can help minimize irritation.

Is Tretinoin safe for long-term use?

Yes, Tretinoin is safe for long-term use when applied as directed by your dermatologist. Many patients continue using it as a maintenance therapy to prevent acne recurrence and improve skin texture.

Does Tretinoin make the skin more sensitive to the sun?

Yes, Tretinoin increases photosensitivity, making sunscreen use essential to prevent sunburn and further skin damage.